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Joined 1 year ago
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Cake day: June 30th, 2023

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  • (Slight) hyperbole aside, it seems like a week doesn’t go by without reading about another brown child or teenager being aged up when the capitalist owned media wants to run cover for wanton government violence against them. This is from the same rotten root that leads to black, indigenous, and immigrant children in the US getting long prison sentences (and in the past, executed) after being tried as adults for crimes that, if they were white, would much more likely see them tried in juvenile court.

    Sorry for veering off topic, I happened to recently read a paper on disparities in the US judicial process by race for juvenile defendants, and needed to vent.



  • Fascists trying to pit marginalized groups against each other. Classic move, but kind of played out at this point.

    When people have compassion and empathy for oppressed people’s suffering, the right thing to do is help them survive and end the suffering, full stop. There may be an added benefit later on where individuals become more compassionate themselves as a result, but that is not the primary goal - just a really nice bonus we get sometimes.

    This artist still thinks he can help divide & conquer people with shit like this, but it’s weak af in today’s environment. Our younger generations see right through it.


  • I have an Astell & Kern SR25 MKII DAP (digital audio player) and I use it quite frequently. The sound quality far surpasses what my phone can produce when connected to any of my speakers or headphones.

    It plays FLAC files and any other audio file type you can think of. And it acts as an offline music library when needed (64 GB of memory plus a 1TB microSD).

    The better the headphones/speakers I use, the more it outshines anything coming out of my other electronic devices. I use it almost every day.




  • "Drivers have long raised the insufferable heat they can face when out for a day of deliveries, especially in the hotter parts of the country. The fleet of UPS trucks doesn’t have any air conditioning to keep the drivers safe and comfortable during their long hours on the job. During the summer months, package cars can reach upwards of 130 F. This has led to far too many UPS drivers suffering from heat stroke on the job, and some have even died due to the excessive heat. With worsening global warming, these issues will only become more severe. "

    This is why we need unions and direct action more than ever, and can’t rely on government entities (ultimately beholden to capitalist interests) to protect our health and safety while we’re on the job. What the fuck good is OSHA if it is allowing heat illness and heat stroke deaths to happen without holding UPS accountable? They should have had their operations shut down until they outfit every truck with AC, and be fined into oblivion until they do so. Instead, OSHA does squat. Health & safety regulations are written in blood but OSHA’s bloody hands refuse to even touch the paper.


  • You are saying that sucralose (or a metabolite thereof) could alkylate DNA - and theoretically proteins too - correct? Like what sulfur mustard gas does?

    I did a quick search and couldn’t find any papers demonstrating a mechanism of action for that, although I skimmed a few that postulated that a dichlorinated hydrolysis product might be the true carcinogenic agent. Do you know of any studies that demonstrate that the alkylation can happen, either in vitro or (ideally) in vivo? Or maybe some better search terms to use, that could be my issue…

    I am truly curious about this, I never knew the chemical structure of sucralose until I read your comment and subsequently looked it up.



  • Very interesting articles - both the phys.org one and journal submission it describes. I appreciate the research group’s use of solvent-free and one-pot reactions wherever possible, it really shows their commitment to finding the most sustainable overall process.

    The aromatization steps using palladium (0) are of course standard processes used by the oil refining industry, but I wonder if there are other methods (maybe using sulfur?) that don’t involve the use of rare metals…probably wouldn’t have the same atom economy as using catalytic Pd though, I am just curious rather than criticizing their choice.