• BarrelAgedBoredom@lemm.ee
    link
    fedilink
    English
    arrow-up
    34
    arrow-down
    13
    ·
    edit-2
    11 months ago

    Not to mention the pharmacological effects of methamphetamine are indistinguishable from Adderall when taken orally in similar doses

    E: I was misremembering this study. It was measuring the physiological and behavioral effects of insufflated amphetamines, not oral. Here’s a vice article with additional info from the doctor who conducted the study

    • circuscritic@lemmy.ca
      link
      fedilink
      English
      arrow-up
      28
      arrow-down
      4
      ·
      edit-2
      11 months ago

      This is objectively false.

      Setting aside the issue of QA and how and in what conditions this methamphetamine is being produced, no, the pharmacological effects of methamphetamine are NOT just the same as Adderall (blend of 4 different amphetamine salts).

      It’s also not prescribed for ADHD, except in rare circumstances. It’s mostly prescribed for conditions like narcolepsy, because it’s significantly more psychoactive then amphetamine salts, and that’s BEFORE you factor in issue of these being cartel produced counterfeit pressed meth pills vs production in an actual pharmaceutical laboratory with the accompanying conditions and controls.

      • BarrelAgedBoredom@lemm.ee
        link
        fedilink
        English
        arrow-up
        9
        arrow-down
        11
        ·
        11 months ago

        Im not telling people to buy crank from some dude down the street instead of going to the pharmacy for their Adderall. You’re just putting words in my mouth and getting mad at them.

        However, I was misremembering a study I read a few years ago. Outside of in vitro and rat studies, I couldn’t find anything measuring the pharmacological effects of Adderall and meth. I should’ve said behavioural and physiological instead. It was intranasal instead of oral as well, for what that’s worth. The behavioral effects are essentially identical and there are very minor differences in effects on heart rate and blood pressure. I will be correcting my comment after I reply to you.

        • circuscritic@lemmy.ca
          link
          fedilink
          English
          arrow-up
          8
          arrow-down
          2
          ·
          11 months ago

          I put no words in your mouth. I took your response, briefly explained why it was wrong, and then further expanded on why it was dangerous.

          Your words:

          Not to mention the pharmacological effects of methamphetamine are indistinguishable from Adderall when taken orally in similar doses

          • BarrelAgedBoredom@lemm.ee
            link
            fedilink
            English
            arrow-up
            9
            arrow-down
            2
            ·
            11 months ago

            And what part of that mentioned anything about sourcing meth from the streets? As far as my intentions are concerned, I was speaking strictly pure, prescribed methamphetamine, taken as prescribed. That could’ve been inferred from context since the comment I was replying to was about how methamphetamine is sometimes prescribed for ADHD. The conversation wasn’t about street drugs and until you commented, no one brought it up

            • circuscritic@lemmy.ca
              link
              fedilink
              English
              arrow-up
              6
              arrow-down
              3
              ·
              edit-2
              11 months ago

              No worries, I didn’t realize that you hadn’t actually read the article before making your comments.

              So, you can disregard my comments where I had incorrectly assumed we both actually read the linked LA Times story.

              My other comments about how it’s factually incorrect to say methamphetamine and Adderall are the same, those are still in bounds. Right?

              Just FYI counterfeit pills sold in Mexico are either made by the cartels, or they’re fake placebo bullshit (both types are mentioned in said article).

              • BarrelAgedBoredom@lemm.ee
                link
                fedilink
                English
                arrow-up
                4
                arrow-down
                4
                ·
                11 months ago

                Forgot what the thread was originally about lol, my bad. I skimmed the article, I’m working and haven’t given it a proper read yet. I see why you were saying all that now, that’s on me and I apologize.

                To say they’re the same is incorrect as they are different compounds. But if we’re judging them on their effects on the mind and body, taken the same way and in the same doses; they illicit a nearly identical response. If you accidentally took a meth pill instead of Adderall, it’s likely you would only notice minor differences if you noticed anything

    • banneryear1868@lemmy.world
      link
      fedilink
      English
      arrow-up
      11
      arrow-down
      2
      ·
      edit-2
      11 months ago

      I can vouch for this as someone who’s tried equivalent doses of each, less methamphetamine is required to achieve the same effects but I couldn’t tell the difference. Compared with the recreational forms you’re also dealing with different salts combined in the prescription. This sentiment is also common.

      • BarrelAgedBoredom@lemm.ee
        link
        fedilink
        English
        arrow-up
        8
        arrow-down
        2
        ·
        11 months ago

        Turns out I was misremembering a study I read a few years back. It was intranasal, not oral. They’re still incredibly similar in their effects at the same dose. Here’s the study. And a vice article about the study with commentary from the doctor who conducted it.