• jadero@mander.xyz
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    4 months ago

    Interesting. One of the chemicals they reference is tetrachloroethylene. According to this Wikipedia article:

    Perhaps the greatest use of TCE is as a degreaser for metal parts. It has been widely used in degreasing and cleaning since the 1920s because of its low cost, low flammability, low toxicity and high effectivity as a solvent. The demand for TCE as a degreaser began to decline in the 1950s in favor of the less toxic 1,1,1-trichloroethane. However, 1,1,1-trichloroethane production has been phased out in most of the world under the terms of the Montreal Protocol, and as a result, trichloroethylene has experienced some resurgence in use as a degreaser.[17]

    My grandfather had Parkinson’s. I would imagine that he had plenty of exposure in his work as a mechanic from about 1925 on.

  • Paragone@mander.xyz
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    4 months ago

    Tell that to the people who get Parkinson’s from their psychiatric-meds, who then have to take meds to counter the Parkinson’s that their other meds is creating in them.

    • Ranvier@sopuli.xyz
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      4 months ago

      Saying you get Parkinson’s disease from anti psychotics is a gross over simplification that is basically untrue. Yes they are dopamine depleting drugs, so some of the side effects (which unfortunately can persist even after stopping the drugs in some cases when used over extended periods) are similar to symptoms of Parkinson’s disease. Usually doctors will use the word “parkinsonism” to make clear they mean some of the movement symptoms from dopamine depletion like Parkinson’s disease, but not Parkinson’s itself.

      Parkinson’s disease is caused by the toxic buildup of alpha synuclein bodies in many different centers of the brains, including centers that make dopamine but many more as well, eventually resulting in severe dementia in the end. That is not what is happening when people who take anti psychotic medications get parkinsonism symptoms.

      The terminology gets quite confusing, but just want to be clear that while anti psychotic medications can sometimes cause Parkinson’s like symptoms (parkinsonism), it is not a cause of Parkinson’s disease itself.

      https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(14)00214-4